Liver transplantation for cardiac failure in patients with hereditary hemorrhagic telangiectasia.
نویسندگان
چکیده
Liver involvement in hereditary hemorrhagic telangiectasia may lead to high-output cardiac failure. Few data have been reported on orthotopic liver transplantation (OLT) for these patients. In this paper, we describe two patients treated by OLT as a salvage procedure for cardiac failure, and we review literature on this subject. Our two patients resumed normal cardiac function after OLT. This procedure appears to be a promising therapy with good long-term results despite dissection difficulties encountered due to the collateral arterial network reorganization.
منابع مشابه
Bevacizumab reverses need for liver transplantation in hereditary hemorrhagic telangiectasia.
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease characterized by mucocutaneous and visceral telangiectasia. Hepatic involvement with vascular malformations may lead to portal hypertension, biliary ischemia, and high-output cardiac failure. Liver transplantation is indicated for life-threatening disease but carries significant risk from surgery and chronic immunosupp...
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Liver involvement in hereditary hemorrhagic telangiectasia (HHT) can lead to high output heart failure. We report a case of a patient with HHT who developed high output heart failure that failed to respond to maximal medical therapy who eventually underwent liver transplantation with resolution of symptoms.
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ورودعنوان ژورنال:
- Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
دوره 11 7 شماره
صفحات -
تاریخ انتشار 2005